Deflux injection is injected submucosally in the urinary bladder in close proximity to the ureteral orifice. The injection of deflux creates increased tissue bulk thereby providing coaptation of the distal ureter during filling and contraction of the bladder. The dextranomer microspheres are gradually surrounded by host connective tissue.
Deflux is a sugar-based medicine (a polysaccharide) used to treat vur. It is injected through the cystoscope at the site of the vur, where the ureters open into the bladder. A deflux injection prevents urine from flowing back up the ureters from the bladder.