CARBAGLU (carglumic acid) is a prescription drug used in all ages to help treat a rare inherited disorder called NAGS deficiency, a lack or shortage of NAGS enzyme activity, which leads to high blood ammonia levels (hyperammonemia).
CARBAGLU is used to supplement treatment of acute hyperammonemia due to the lack or shortage of the NAGS enzyme. Other ammonia lowering therapies such as other medications, hemodialysis and limiting protein in the diet are recommended during an acute episode.
CARBAGLU is used to maintain normal blood ammonia levels in children and adults with NAGS deficiency. During maintenance therapy, the use of other ammonia lowering therapies and limiting protein may be needed based on plasma ammonia levels.